博士，教授

基因组与个体化医学研究中心

医学实验中心

教育部区域性高发肿瘤早期防治研究重点实验室

个人简历：

      2006.3-2009.9，上海交通大学农业与生物学院，生物医学工程，博士

     2000.9-2003.7， 广西师范大学生命科学院，生态学，硕士

     1996.9-2000.7，安徽淮北师范大学，生物教育，学士
 

研究工作经历：

      2009.11-至今，广西医科大学，教授

     2003.7-2006.3，广西药用植物研究所，科研发展科，实习研究员

专著：

      主编：李力、胡艳玲，《实用医学分子生物信息学教程》，广西科学技术出版社，322千字，2013.12

软件著作权：

      申请5部软件著作权，其中2部为第一完成人，3部为博士期间开发的软件，排名第二。

[1] 胡艳玲，辛先祥，陈阳，黄俏莹，蒋心，陈盘余，顾殷敏. 多性状与基因组多区域多位点关联分析软件V1.0[简称：MHLasso] 软件著作权号: 2013R11L252318.
[2] 胡艳玲，龙建雄，梁斯巧，庞凤，苏莉，等. 基于文本挖掘的医学信息数据库查询系统[简称：医学信息数据库查询系统]V1.0. 软件著作权授权号：2012SR122159，授权国家：中国.
[3] 潘玉春，胡艳玲，王起山, 赵洪波，张向，黄明辉等. 基因组多区域单倍体型联合分析软件V1.0(简称:HAPGLM). 软件著作权授。权号：2009SR07478,授权国家：中国.
[4] 潘玉春，胡艳玲，王起山, 赵洪波，张向，黄明辉等. 动态性状单倍体型联合分析软件V1.0(简称:HAPGAMM). 件著作权授权号：2009SR07479，授权国家：中国.
[5] 潘玉春，胡艳玲，张向, 赵洪波，张向，黄明辉等. 复杂性状与基因组多位点关联分析软件V1.0[简称：Genome.stats] . 软件著作权（2010SR010434）,授权国家：中国.

科研项目：

      目前主持的课题7项，总经费126万元，其中国家级课题3项，经费96万元。

[1] 国家自然科学基金面上项目：RTKs/ERK信号通路与前列腺癌的关联分析及风险点生物功能的研究（项目编号：81272853）.
[2] 国家自然科学基金：基于多性状与基因组多区域多位点关联分析构建人前列腺癌遗传效应信息数据库（项目编号：81060213）.
[3] 中国博士后科学基金：ErbB家族多态性与前列腺癌的关联分析及风险点功能研究（项目编号：2012M511886）.
[4] 广西自然科学基金：基于复杂性状与基因组多区域多位点关联分析构建人前列腺癌遗传效应信息数据库（项目编号：2011GXNSFB018100）.
[5] 广西自然科学基金：不同种族前列腺癌 GWAs  共同相关基因NKX3.1/MSMB/HNF1B 表达调控的研究（项目编号：2012GXNSFAA053152）.
[6] 广西科学研究与技术开发计划项目：多囊卵巢综合征遗传机理的研究及临床应用（项目编号：81060213）.
[7] 广西医学科学实验中心重点实验室开放课题：采用组织工程技术构建体外和体内新型人前列腺癌雄激素非依赖模型（项目编号：KFJJ2011-22）.

论文发表：

      近年来发表文章60余篇，其中SCI论文近40篇。以第一作者/共同第一作者/通讯作者发表于PLoS Genet （IF=8.517），Hum Mol Genet（IF=7.636）, Eur J Hum Genet (IF=4.4), PLoS ONE（IF=3.73）等杂志上的SCI论文21篇，总IF达50.315，总引用51次。主要集中于前列腺疾病相关的分子生物学和生物信息学的研究。

[1] Chen Y, Xin X, Li J, Xu J, Yu X, Li T, Mo Z*, Hu Y*. RTK/ERK Pathway under Natural Selection Associated with Prostate Cancer. PLoS One. 8(11):e78254. 2013.（IF=3.73）
[2] Liu Y, He W, Long J, Pang F, Xian L, Chen M, Wu Y, Hu Y*. Natural selection and functional diversification of the epidermal growth factor receptorEGFR family in vertebrates. Genomics. 101(6):318-25. 2013.（IF=3.01）
[3] Chen Y, Li T, Yu X, Li J, Luo D, Mo Z*, Hu Y*. The RTK/ERK pathway is associated with prostate cancer risk on the SNP level: A pooled analysis of 41 sets of data from case-control studies. Gene. 534(2):286-97. 2013.(IF=2.196)
[4] Chen Y, Li J, Yu X, Li S, Zhang X, Mo Z*, Hu Y*. APC gene hypermethylation and prostate cancer: a systematic review and meta-analysis. Eur J Hum Genet. 21(9):929-35. 2013.(IF=4.4)
[5] Hu YL, Zhong D, Pang F, Ning QY, Zhang YY, Li G, Wu JZ, Mo ZN*. HNF1b is involved in prostate cancer risk via modulating androgenic hormone effects and coordination with other genes. Genet Mol Res. 25;12(2):1327-35. 2013.(IF= 1.184)
[6] Yang X, Sun J, Gao Y, Tan A, Zhang H, Hu Y（共一）, Feng J, Qin X, Tao S, Chen Z, Kim ST, Peng T, Liao M, Lin X, Zhang Z, Tang M, Li L, Mo L, Liang Z, Shi D, Huang Z, Huang X, Liu M, Liu Q, Zhang S, Trent JM, Zheng SL, Xu J, Mo Z*. Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects. PLoS Genet. 8(9):e1002916. 2012.(IF=8.517)
[7] Tan A, Sun J, Xia N, Qin X, Hu Y（共一）, Zhang S, Tao S, Gao Y, Yang X, Zhang H, Kim ST, Peng T, Lin X, Li L, Mo L, Liang Z, Shi D, Huang Z, Huang X, Liu M, Ding Q, Trent JM, Zheng SL, Mo Z*, Xu J. A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population. Hum Mol Genet. 1;21(7):1658-64. 2012. (IF=7.692)
[8] Ning QY, Wu JZ, Zang N, Liang J, Hu YL*, Mo ZN. Key pathways involved in prostate cancer based on gene set enrichment analysis and meta analysis. Genet Mol Res. 10(4):3856-87. 2011. (IF= 1.184)
[9] Hu Y, Jason S, Wang Q, Pan Y, Zhang X, Zhao H, Li C, Sun L. Regression-based approach for testing the association between multi-region haplotype configuration and complex trait. BMC Genet. 10:56. 2009.（IF= 2.808）
[10] Li J, Chen Y, Liu C, Hu Y*, Li L*. Intravenous Immunoglobulin Treatment for Repeated IVF/ICSI Failure and Unexplained Infertility: A Systematic Review and a Meta-Analysis. Am J Reprod Immunol. 70(6):434-47. 2013.（IF= 3.317）
[11] Li J, Chen Y, Wei SX, Wu HB,  Liu CJ, Huang QY, Li LM*, Hu YL*.Tumor Necrosis Factor and Interleukin-6 Gene Polymorphisms and Endometriosis Risk in Asians: A Systematic Review and Meta-Analysis. Annals of Human Genetics. 78(2):104-16. 2013.(IF= 2.215)
[12] Hu Y, Zhang Y, He W, Xian L, Chen M*. NQO1 C609T polymorphism and esophageal cancer risk: a HuGE review and meta-analysis. BMC Med Genet. 14:31. 2013.( IF=2.536)
[13] Gu L, Wu G, Long J, Su L, Yan Y, Chen Q, Xie J, Hu Y*. The role of TNF-α 308G>A polymorphism in the risk for ischemic stroke. Am J Med Sci. 345(3):227-33 .2013.(IF= 1.334)
[14] Zeng Z, Que T, Zhang J, Hu Y*. A study exploring critical pathways in clear cell renal cell carcinoma. Exp Ther Med. 7(1):121-130. 2014.(IF= 0.344)
[15] Yang Chen, Jie W, Yanlong Y, Xuefeng G, Aihua T, Yong G, Zheng L, Youjie Z, Haiying Z, Xue Q, Min Q, Linjian M, Xiaobo Y, Yanling H*, Zengnan M*. Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers. Immunogenetics. 64(10):747-53. 2012.(IF= 2.894)
[16] Liu Z, Hu Y（共一）, Yang X, Tan A, Gao Y, Qin X, Liang Y, Mo Z*, Peng T*.  Combinative analysis of factors influence serum alanine aminotransferase activity in adult male population from southern China. Clin Biochem. 45(18):1683-8. 2012.
[17] Xian L, He W, Pang F, Hu Y*. ADIPOQ gene polymorphisms and susceptibility to polycystic ovary syndrome: a HuGE survey and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 161(2):117-24. 2012.（IF= 1.843）
[18] Yang C, Fangfang W, Jie L, Yanlong Y, Jie W, Xuefei L, Xuerong Z, Yanling H* . Angiotens in-converting enzyme insertion/deletion (I/D) polymorphisms and recurrent pregnancy loss: a meta-analysis. J Assist Reprod Genet. 29(11):1167-73. 2012.（IF= 1.823）
[19] He W, Long J, Xian L, Pang F, Su L, Wei S, Wei B, Hu Y*. MDM2 SNP309 polymorphism is associated with lung cancer risk in women: A meta-analysis using METAGEN. Exp Ther Med. 4(4):569-576. 2012.（IF=0.344）
[20] Gu L, Yan Y, Long J, Su L, Hu Y*, Chen Q, Xie J, Wu G.2012.The TNF-α-308G/A polymorphism is associated with migraine risk: A meta-analysis. Exp Ther Med. 3(6):1082-1086. 2012. （IF=0.344）
[21] Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS. Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO. Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet. 44(3):307-11. 2012.（IF= 35.209）
[22] M. Wang, F. Liu, A.W. Hsing, X. Wang, Q. Shao, J. Qi, Y. Ye, Z. Wang, H. Chen, X. Gao, G. Wang, L.W. Chu, Q. Ding, J. OuYang, Y. Huang, Y. Chen, Y.T. Gao, Z.F. Zhang, J. Rao, R. Shi, Q. Wu, Y. Zhang, H. Jiang, J. Zheng, Y. Hu, L. Guo, X. Lin, S. Tao, G. Jin, J. Sun, D. Lu, S.L. Zheng, Y. Sun, Z. Mo*, C. Yin*, Z. Zhang*, J. Xu*. Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case-control study in the ChinaPCa consortium. Carcinogenesis. 3:3356-360.2012.(IF= 5.635)
[23] J. Zheng, F. Liu, X. Lin, X. Wang, Q. Ding, H. Jiang, H. Chen, D. Lu, G. Jin, A.W. Hsing, Q. Shao, J. Qi, Y. Ye, Z. Wang, X. Gao, G. Wang, L.W. Chu, J. Ouyang, Y. Huang, Y. Chen, Y. Gao, R. Shi, Q. Wu, M. Wang, Z. Zhang, Y. Hu, J. Sun, S.L. Zheng, C. Xu, Z. Mo*, Y. Sun*, J. Xu*. Predictive performance of prostate cancer risk in Chinese men using 33 reported prostate cancer risk-associated SNPs. Prostate. 72: 577-583.2012.(IF= 3.843)
[24] F. Liu, A.W. Hsing, X. Wang, Q. Shao, J. Qi, Y. Ye, Z. Wang, H. Chen, X. Gao, G. Wang, L.W. Chu, Q. Ding, J. OuYang, Y. Huang, Y. Chen, Y.T. Gao, Z.F. Zhang, J. Rao, R. Shi, Q. Wu, M. Wang, Z. Zhang, Y. Zhang, H. Jiang, J. Zheng, Y. Hu, L. Guo, X. Lin, S. Tao, G. Jin, J. Sun, D. Lu, S.L. Zheng, Y. Sun, Z. Mo*, J. Xu*. Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men. Cancer science. 102:1916-1920. 2011.(IF= 3.479)
[25] Zhong D, Li G, Long J, Wu J, Hu Y*. The hOGG1Ser326Cys polymorphism and increased lung cancer susceptibility in Caucasians: an updated meta-analysis. Sci Rep. 2012;2:548. 2012.（SCI收录）
[26] Chen Z, Tao S, Gao Y, Zhang J, Hu Y, Mo L, Kim ST, Yang X, Tan A, Zhang H, Qin X, Li L, Wu Y, Zhang S, Zheng SL, Xu J, Mo Z*, Sun J*. Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men. J Med Genet. 50(12): 794-801. 2013.（IF= 5.703）
[27] Xie Y, Wang M, Zhang Y, Zhang S, Tan A, Gao Y, Liang Z, Shi D, Huang Z, Zhang H, Yang X, Lu Z, Wu C, Liao M, Sun Y, Qin X, Hu Y, Li L, Peng T, Li Z, Yang X, Mo Z*. Serum uric acid and non-alcoholic fatty liver disease in non-diabetic Chinese men. PLoS One. 8(7):e67152. 2013.(IF=3.73)
[28] Zhang Y, Zhang S, Gao Y, Tan A, Yang X, Zhang H, Wu C, Lu Z, Liao M, Xie Y, Zhang Z, Qin X, Yu X, Li L, Hu Y, Mo Z*. Factors associated with the pressure pain threshold in healthy Chinese men. Pain Med. 14(9):1291-300. 2013.(IF= 2.459)
[29] Zhang J, Huang X, Liao M, Gao Y, Tan A, Yang X, Zhang H, Mo L, Zhang Y, Lu Z, Wu C, Hu Y, Mo Z*. Both total testosterone and sex hormone-binding globulin are independent risk factors for metabolic syndrome: results from Fangchenggang Area Male Health and Examination Survey in China. Diabetes Metab Res Rev. 29(5):391-7. 2013.(IF= 2.968)
[30] He M, Wu C, Xu J, Guo H, Yang H, Zhang X, Sun J, Yu D, Zhou L, Peng T, He Y, Gao Y, Yuan J, Deng Q, Dai X, Tan A, Feng Y, Zhang H, Min X, Yang X, Zhu J, Zhai K, Chang J, Qin X, Tan W, Hu Y, Lang M, Tao S, Li Y, Li Y, Feng J, Li D, Kim ST, Zhang S, Zhang H, Zheng SL, Gui L, Wang Y, Wei S, Wang F, Fang W, Liang Y, Zhai Y, Chen W, Miao X, Zhou G, Hu FB, Lin D, Mo Z*, Wu T*. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk. Gut. 63(1):143-51. 2014.(IF= 10.732)
[31] Sun J, Tao S, Gao Y, Peng T, Tan A, Zhang H, Yang X, Qin X, Hu Y, Feng J, Kim ST, Lin X, Wu Y, Zhang J, Li Z, Li L, Mo L, Liang Z, Shi D, Huang Z, Huang X, Liu M, Liu Q, Zhang S, Lilly Zheng S, Xu J*, Mo Z*. Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population. Hum Genet. 132(4):423-9. 2013.(IF= 4.633)
[32] Yang M, Wu Y, Lu Y, Liu C, Sun J, Liao M, Qin M, Mo L, Gao Y, Lu Z, Wu C, Zhang Y, Zhang H, Qin X, Hu Y, Zhang S, Li J, Dong M, Zheng SL, Xu J, Yang X, Tan A, Mo Z*. Genome-wide scan identifies variant in TNFSF13 associated with serum IgM in a healthy Chinese male population. PLoS One. 2012;7(10):e47990. 2012.(IF=3.73)
[33] Li J, Long J, Hu Y, Tan A, Guo X, Zhang S*. Glutathione S-transferase M1, T1, and P1 polymorphisms and thyroid cancer risk: a meta-analysis. Cancer Epidemiol. 36(6):e333-40. 2012.(IF= 2.232)
[34] Lin X, Lu D, Gao Y, Tao S, Yang X, Feng J, Tan A, Zhang H, Hu Y, Qin X, Kim ST, Peng T, Li L, Mo L, Zhang S, Trent JM, Mo Z, Zheng SL*, Xu J*, Sun J*. Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men. Hum Mol Genet. 21(11):2610-7. 2012.(IF= 7.692)
[35] Zhang Y, Gao Y, Tan A, Yang X, Zhang H, Zhang S, Wu C, Lu Z, Wang M, Liao M, Qin X, Li L, Hu Y, Mo Z*. Endogenous sex hormones and C-reactive protein in healthy Chinese men. Clin Endocrinol (Oxf).78(1):60-6. 2013.(IF= 3.396)
[36] Gao Y, Wang M, Zhang H, Tan A, Yang X, Qin X, Hu Y, Zhang Y, Liao M, Mo Z*. Are metabolic syndrome and its components associated with lower urinary tract symptoms? Results from a Chinese male population survey. Urology.79(1):194-201. 2012.（IF= 2.424）
[37] Lu Z, Gao Y, Tan A, Yang X, Zhang H, Mo L, Wu C, Hu Y, Mo Z*. Increased high-sensitivity C-reactive protein predicts a high risk of lower urinary tract symptoms in Chinese male: Results from the Fangchenggang Area Male Health and Examination Survey. Prostate. 72(2):193-200. 2012. (IF=3.843)
[38] Liao M, Shi D, Wang Y, Zhang K, Chen X, Gao Y, Tan A, Xuan Q, Yang X, Hu Y, Qin X, Zhang H, Mo Z*. Genome-wide scan on total serum IgE levels identifies no common variants in a healthy Chinese male population. Immunogenetics. 65(8):561-8. 2013.（IF= 2.894）
[39] Liao M, Ye F, Zhang B, Huang L, Xiao Q, Qin M, Mo L, Tan A, Gao Y, Lu Z, Wu C, Zhang Y, Zhang H, Qin X, Hu Y, Yang X, Mo Z*. Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population.Genes Immun. 13(6):509-13, 2012.(IF= 3.675)